16.11.06 News From Salk

DNA Repair Teams' Motto: 'To Protect and Serve'

 

When you dial 911 you expect rescuers to pull up to your front door, unload and get busy not park the truck down the street and eat doughnuts. The same holds true for a cell, which recruits protein complexes to repair DNA breakage after division. A previous Salk study revealed that some of these cellular paramedics inexplicably idle at undamaged chromosome ends. Now the same research team, led by Jan Karlseder, assistant professor in the Molecular and Cell Biology Laboratory, explains why those repair crews stay put and in doing so answer fundamental questions about how chromosomal stability is maintained.

 

 

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Press Release Jan Karlseder