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Mònica Díaz Ferrer

Mònica Díaz Ferrer

Mònica Díaz holds a bachelor degree in Biochemistry and a PhD in Physiology from the University of Barcelona. During the PhD she studied the role of insulin regulating the glucose transport in skeletal muscle under the supervision of Dr Josep Planas. After finishing her PhD she stayed at the same laboratory as a postdoctoral researcher and assistant professor for one year.
In 2008, she did a short stay as postdoctoral researcher in CIBBIM-Nanomedicine at the Vall d'Hebron Research Institute, in the laboratory of Dr Julián Cerón that was focused on the modeling of human diseases in C. elegans.

Then she moved to Omnia Molecular, a biotech company devoted to the design and development of new anti-infectives targeted at difficult-to-treat infections, as a project manager. She participated in the setup and development of a proprietary technology platform. Among her tasks, she was in charge of the cell-based assays, in particular their design and miniaturization to be incorporated into a high-throughput screening campaign.

In 2013, she joined the CMR[B] as a research assistant. Here, she is involved in several projects aimed to model in vitro different diseases through the generation of patient-derived pluripotent stem cells.

Selected Publications

  • Calatayud C, Carola G, Fernández-Carasa I, Valtorta M, Jiménez-Delgado S, Díaz M, Soriano-Fradera J, Cappelletti G, García-Sancho J, Raya Á, Consiglio A. (2019) CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons. Sci Rep 9(1):6811.
  • Goetz FW, Planas JV, Díaz M, Iliev DB, MacKenzie S. (2012) Culture of Fish Head Kidney Mononuclear Phagocytes and Muscle Satellite Cells: Valuable Models for Aquaculture Biotechnology Research. Aquaculture Biotechnology. Ed. Wiley-Blackwell. United Kingdom; p. 207-221. ISBN: 978-0-8138-1028-7.
  • Vraskou Y, Roher N, Díaz M, Antonescu CN, MacKenzie S, Planas JV. (2011) Direct involvement of tumor necrosis factor-alpha in the regulation of glucose uptake in rainbow trout muscle cells. Am J Physiol Regul Integr Comp Physiol 300(3): R16-R23.
  • Capilla E, Díaz M, Hou JC, Planas JV, Pessin JE. (2010) High basal cell surface levels of fish GLUT4 are related to reduced sensitivity of insulin-induced translocation toward GGA and AS160 inhibition in adipocytes. Am J Physiol Endocrinol Metab 298(2): E329-E336.
  • Castillo J, Crespo D, Capilla E, Díaz M, Chauvigné F, Cerdà J, Planas JV. (2009) Evolutionary structural and functional conservation of an ortholog of the GLUT2 glucose transporter gene (SLC2A2) in zebrafish. Am J Physiol Regul Integr Comp Physiol 297(5): R1570-R1580.
  • Díaz M, Vraskou Y, Gutiérrez J, Planas JV. (2009) Expression of rainbow trout glucose transporters GLUT1 and GLUT4 during in vitro muscle cell differentiation and regulation by insulin and IGF-I. Am J Physiol Regul Integr Comp Physiol 296(3): R794-R800.
  • Antonescu CN, Díaz M, Femia G, Planas JV, Klip A. (2008) Clathrin-dependent and independent endocytosis of glucose transporter 4 (GLUT4) in myoblasts: regulation by mitochondrial uncoupling. Traffic 9(7): 1173-1190.
  • Roher N, Samokhvalov V, Díaz M, MacKenzie S, Klip A, Planas JV. (2008) The proinflammatory cytokine TNF-alpha increases the amount of GLUT4 at the surface of muscle cells independently of changes in IL-6. Endocrinology 149: 1880-1889.
  • Díaz M, Antonescu CN, Capilla E, Klip A, Planas JV. (2007) Fish GLUT4 differs from rat GLUT4 in its traffic characteristics but can translocate to the cell surface in response to insulin in skeletal muscle cells. Endocrinology 148: 5248-5257.
  • Roher N, Díaz M, MacKenzie S, Krasnov A, Planas JV. (2007) Aproximaciones genómicas al crecimiento y nutrición en peces. Genética y genómica en acuicultura (Eds. J. Espinosa; Coord: P. Martínez and A. Figueras). Editorial Consejo Superior de Investigaciones Científicas. Madrid; p. 621-659. ISBN: 978-84-00-08553-7.
  • Díaz M, Capilla E, Planas JV. (2007) Physiological regulation of glucose transporter (GLUT4) protein content in brown trout (Salmo trutta) skeletal muscle. J Exp Biol 210: 2346-2351.
  • Navarro I, Capilla E, Castillo J, Albalat A, Díaz M, Gallardo MA, Blasco J, Planas JV, Gutiérrez J. (2006) Insulin metabolic effects in fish tissues. Fish Endocrinology. Eds. G. Zaccone, M. Reinecke and B.G. Kapoor. 100378-Kapoor Science publishers, Inc. Enfield (NH), Plymouth, USA; p. 15-48. ISBN: 1-57808-318-4.
  • Navarro I, Castillo J, Albalat A, Codina M, Rojas P, Díaz M, Pérez-Sánchez J, Planas JV, Gutiérrez J. (2005) Control endocrino del metabolismo en miocitos y adipocitos de peces teleósteos. Avances en Endocrinología Comparada, Vol. II. Eds. J. P. Castaño, M. M. Malagón and S. García Navarro. Serv. Publ. Univ. Córdoba. ISBN: 84-7801-757-7.
  • Capilla E, Díaz M, Albalat A, Navarro I, Pessin JE, Keller K, Planas JV. (2004) Functional characterization of an insulin-responsive glucose transporter (GLUT4) from fish adipose tissue. Am J Physiol Endocrinol Metab 287: E348-E357.
  • Capilla E, Díaz M, Gutiérrez J, Planas JV. (2002) Physiological regulation of the expression of a GLUT4 homolog in fish skeletal muscle. Am J Physiol Endocrinol Metab 283: E44-E49.

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