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Francesca Matteini

Francesca Matteini

Francesca Matteini obtained her bachelor degree in biological sciences in 2012 at University of Florence. During this period she studied the effect of cosmic radiation on hereditary material after its exposure to extraterrestrial environment.

She followed her studies obtaining her master degree in cellular and molecular biology at University of Florence in 2015. During her master’s internship she worked on the characterization of the autocrine and paracrine action of bone marrow-derived Mesenchymal Stromal Cells, focusing on role of sphingolipids.

From October 2015 to February 2019 Francesca performed her PhD in human biology and medical genetics at Sapienza University of Rome. During her PhD Francesca studied the role of the Poly(ADP-ribose)polymerase 1 (PARP1) in the transcriptional regulation of MyoD target genes.

Francesca joined the Center of Regenerative Medicine in Barcelona (CMRB) in March 2019 first with an Erasmus+ Unipharma Graduates scholarship and then as postdoctoral researcher in Dr. Carolina Florian’s group, focusing on the role of the bone marrow niche in the regulation of HSCs function upon aging.

Selected Publications

Andresini O., Rossi M.N., Matteini F., Petrai S. and Maione R. (2019) The Long non-coding RNA Kcnq1ot1 regulates maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region. Epigenetics Chromatin 12(1):8.

Pierucci F., Frati A., Battistini C., Matteini F., Iachini M.C., Vestri A., Penna F., Costelli C. and Meacci E. (2018) Involvement of released sphingosine 1-phosphate/sphingosine 1-phosphate receptor axis in skeletal muscle atrophy, Biochim Biophys Acta Mol Basis Dis 1864(12):3598-3614. Epub 2018 Sep 1.

Sassoli C, Pierucci F,Tani A, Frati A, Chellini F, Matteini F, Vestri A, Anderloni G, Nosi D, Zecchi-Orlandini S, Meacci E (2018). Sphingosine 1-Phosphate Receptor 1 Is Required for MMP-2 Function in Bone Marrow Mesenchymal Stromal Cells: Implications for Cytoskeleton Assembly and Proliferation. Stem Cells Int 2018:5034679.

Rossi MN, Andresini O, Matteini F, Maione R. (2018). Transcriptional regulation of p57kip2 expression during development, differentiation and disease, Front Biosci (Landmark Ed) 23:83-108.

Sassoli C., Frati A., Tani A., Andreloni G., Pierucci F., Matteini F., Chellini F., Zecchi Orlandini S., Formigli L. and Meacci E. (2014). Mesenchymal Stromal Cell Secreted Sphingosine1-Phospate (S1P) Exerts a Stimulatory Effect on Skeletal Myoblast Proliferation. Plos One 9(9):e108662.

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